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Sorry if that sounded preachy, your suggestion is 1000% solid, though I'd slot it in with a different card for the CMC to not vary too much, then replace Cryptolith Rite with another ramp spell so that I'm not missing any slots that could otherwise be used, hell, it still bugs me that I have Moonsilver Key and Avacyn, Angel of Hope who is canonically dead and then some, in the same deck. I had this deck kitted out similarly and against my table, without some leeway for proper play, it bricks if I don't hit any ramp. he might have made it Innistrad, the centipede in his card looks the same as what's been printed in Innistrad for sure), Wild Beastmaster (depicting a Selesnya guild member), Growth Spasm feels more akin to this deck's lore and flavor, seeing as Nahiri brought Eldrazi to the plane, and it getting an Innistrad watermark makes it feel a bit more at home, but were I to intentionally make this a Sigardian (good) humans only deck, I'd switch Cryptolith with Fork in the Road, and Growth Spasm with Reclusive Taxidermist or Avacyn's Pilgrim, Descend upon the Sinful with Terminus, Mikaeus, the Lunarch with Hamlet Captain, Wild Beastmaster with Mentor of the Meek and several other cards, but the power just isn't there. The cards I really want to get rid of, if I had Innistrad arts and watermarks to just swap with that'd be even better, but due to lore-specific conflicts Shamanic Revelation (shaman of Tarkir), Unbreakable Formation (Azorius Guildmates from Ravnica), Inspiring Call (Khans of Tarkir), Worldly Tutor (Yisan of Shandalar, but as a wandering bard. I find Cryptolith Rite a suitable spell as it shows what fear drove humans to do, due to Nahiri, the Harbinger and her personal grudge. Cults within churches, Mikaeus, the Lunarch being one of the first humans to turn corrupt for the likes of evil.

I took out Entreat the Angels for Increasing Devotion in favor of humans wanting the deck to very much be human focused, that being that rise and downfall of most of Innistrad. I wish every set was treated like the warhammer commanders, with every card sporting a specific art to the theme of the plane. I've made this deck entirely, foils, pre releases, alt arts and found for the sake of functioning, with the necessity of ramp and draw for the table's I play at, I permitted Tarkir cards like Shamanic Revelation and Inspiring Call because they happened to be printed in the pre-con, but serve little to no use lore wise, sadly. Â Flip blending in to the Cathar churches to recruit cultists, Eldritch Evolution depicting the horror of Emrakul's arrival, I kept Growth Spasm which is a Zendikar set card, only because of its eldrazi involvement, and that it looks eerily similar to Deathbonnet Sprout

This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve.You're not wrong, though with cards like Hanweir Militia Captain We discuss these data in relation to the recent discovery of the direct translation of specific truncated forms of Cx43. We highlight the complex regulatory and signalling networks controlled by the Cx43 CT, including the extensive protein interactome that underlies both gap junction channel-dependent and -independent functions. Here, we review the current understanding of the regulation and unique functions of the Cx43 CT, both as an essential component of full-length Cx43 and as an independent signalling hub. These domains endow Cx43 with the capacity to affect cell growth and differentiation independently of GJIC. Moreover, the Cx43 CT contains multiple domains involved in protein interactions that permit crosstalk between Cx43 and cytoskeletal and regulatory proteins. The long cytosolic C-terminus (CT) of Cx43 is subject to extensive post-translational modifications that modulate its intracellular trafficking and gap junction channel gating. Of the 21 members of the human connexin family, connexin 43 (Cx43) is the most widely expressed and studied. Moreover, several non-canonical connexin functions unrelated to GJIC have been discovered. Gap junctional intercellular communication (GJIC) has important roles in controlling cell growth and differentiation and in tissue development and homeostasis. Connexins are chordate gap junction channel proteins that, by enabling direct communication between the cytosols of adjacent cells, create a unique cell signalling network.